Polydesmidae is a family of millipedes in the order Polydesmida. This family includes species notable for featuring sexual dimorphism in segment number: Adult females in the genus Perapolydesmus have the usual 20 segments (counting the collum as the first segment and the telson as the last), but the adult males have only 19.

- Antrochodus - Archipolydesmus - Basicentrus - Bhutanodesmus - Bidentogon - Bosniodesmus - Bosporodesmus - Brachydesmus - Brembosoma - Calianotus - Chromobrachydesmus - Cookia - Cretodesmus - Dixidesmus - Epanerchodus - Eumastigonodesmus - Goniodesmus - Haplobrachidesmus - Haplocookia - Heterocookia - Himalodesmus - Hispaniodesmus - Huzichodus - Jaxartes - Kirgisdesmus - Leptobrachydesmus - Lophobrachydesmus - Mastigonodesmus - Mastuchus - Merioceratium - Niponchodus - Nipponesmus - Nomarchus - Pacidesmus - Peltogonopus - Perapolydesmus - Polydesmus - Prionomatis - Propolydesmus - Pseudopolydesmus - Retrorsia - Riuerchodus - Sardodesmus - Schedoleiodesmus - Schizobrachydesmus - Schizomeritius - Schizoturanius - Scytonotus - Serradium - Spanobrachium - Speodesmus - Stylobrachydesmus - Telopoditius - Tolosanius - Trachynotus - Troglobrachydesmus - Turanodesmus - Uniramidesmus - Usbekodesmus - Utadesmus